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Mastiff puppies and dogs in Knoxville, Iowa

Looking for a Mastiff puppy or dog in Knoxville, Iowa? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Knoxville, Iowa

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Knoxville, Iowa

These Mastiffs are available for adoption close to Knoxville, Iowa.
We'll also keep you updated on Big E (Ernie)'s adoption status with email updates.
Photo of Big E (Ernie)

Big E (Ernie)

Mastiff

Male, 2 yrs 1 mo
Chariton, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
Big E is a gentle giant who came to us as a stray, and while we’re still getting to know him, one thing is already clear—he’s as sweet as he is big! With his mastiff stature and calm demeanor, Big E is proving to be a laid-back, loving dog who enjoys the company of his people. We’re still learning more about his personality, but so far, Big E has shown nothing but kindness and affection. If you're looking for a big, loving companion who’s sure to make a big impression, Big E might be your perfect match! Stay tuned for more updates as we continue to learn about this lovable boy! Interested in adopting? Please review all adoption requirements listed on our "Adopt" page, including requirements regarding spay/neuter of current pets, regular veterinary care, and home/landlord checks.
We'll also keep you updated on Daisy's adoption status with email updates.
Photo of Daisy

Daisy

Mastiff Terrier (Unknown Type, Medium)

Female, Young
Des Moines, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered, Shots are up-to-date,
Story
Meet Daisy!Daisy is a 1-year-old, 65-pound Mastiff mix with a heart as big as her paws! Rescued as a stray in poor condition, Daisy has been thriving in her foster home and steadily gaining weight. She’s blossomed into a sweet, loving girl who adores bedtime cuddles and following her humans everywhere—they’ll never be alone with her around!Still a playful pup, Daisy has plenty of energy and is house trained and still learning the ropes of training like not jumping on you in excitement. She’s a smart cookie and eager to please, so with patience and consistency, she’ll become an amazing companion. Daisy loves playing with bigger, higher-energy dogs, like her foster family’s huskies, and has shown promise around cats. While she’s still learning to respect feline boundaries, she’s making great progress.Watching Daisy discover toys and grow into her happy, playful self is nothing short of heartwarming. She’s ready to bring her big heart and loyal spirit into a forever home that will love her unconditionally. Could Daisy be your perfect match?IMPORTANT: Please read all below, especially if you live outside of Texas, which is where our rescue is located.Apply to adopt on our website: https://www.charmingpetrescue.org/adoptAll of our animals are spayed/neutered, microchipped, and up to date on shots.ALL of our animals are located in Boerne, TX, but transport after adoption is available to other states for a $300 fee for dogs or an additional fee varying by location for cats. If you are seeing our pets posted in your state, that's because you live near a transport stop, they are not currently at that location. Petfinder lists our pets as 'Out of Town' pets at other locations, and Adopt-a-Pet lists our location as a Transport stop. Those are currently the only options they offer to make this clear, so we put this description we've put at the bottom to explain it. You can read more about transport here: www.charmingpetrescue.org/transportWe understand transport is not an option for everyone, but we offer it at the cost we pay the transport company for those who wish to adopt from us.January 7, 2025, 9:13 pm
We'll also keep you updated on He-Man's adoption status with email updates.
Photo of He-Man

He-Man

Mastiff

Male, Puppy
Urbandale, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
Born March 2019 and was not neutered. He is a great guard dog and has been great with my 2yo and 3yo children their whole lives. He eats Purina One large breed dog food. He is hesitant and will bark at new people until you let him know they are ok. Tall men make him skittish until they sit and he can sniff them. He has never bitten anyone or anything but will bark if strangers make fast movements towards him. Basically a big lovable lap dog that is just 150 lbs. He is very protective of you and your property. Looking for a home that he will be loved and played with since he is active.
We'll also keep you updated on Valentino's adoption status with email updates.
Photo of Valentino

Valentino

Mastiff Labrador Retriever

Male, 6 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Are you looking for a life-long love? I'm sure to make your heart skip a beat with these longing eyes! Hey there, I'm Valentino! I've had a rough start in life as my owners moved and decided to leave my brother and I behind. We don't let it bother us as we know we will find our forever homes soon. We look to be a mix of Mastiff/Lab but the shelter isn't sure. Will you paw-lease adopt me?  If you're interested in adopting me, fill out an adoption application online at www.polkcountyhumanesociety.org/adopt where you will also find a link to reserve me for an appointment. Some pets are in foster homes or may already have an appointment scheduled, so the appointment is important to make sure I will be available to meet you when you come. Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2287925##
We'll also keep you updated on Romeo's adoption status with email updates.
Photo of Romeo

Romeo

Mastiff Labrador Retriever

Male, 6 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Are you looking for a life-long love? I'm sure to make your heart skip a beat with these longing eyes! Hey there, I'm Romeo! I've had a rough start in life as my owners moved and decided to leave my brother and I behind. We don't let it bother us as we know we will find our forever homes soon. We look to be a mix of Mastiff/Lab but the shelter isn't sure. Will you paw-lease adopt me?  If you're interested in adopting me, fill out an adoption application online at www.polkcountyhumanesociety.org/adopt where you will also find a link to reserve me for an appointment. Some pets are in foster homes or may already have an appointment scheduled, so the appointment is important to make sure I will be available to meet you when you come. Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2287932##

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Mastiff shelters & rescues in Knoxville, Iowa

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Knoxville, Iowa. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

23.5 miles

Almost Home Animal Rescue - IA

Chariton, IA 50049

Pet Types: cats, dogs

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Rescue

32.5 miles

Charming Pet Rescue - IA Transport Stop

Des Moines, IA 50309

Pet Types: dogs

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Shelter

38.7 miles

Polk County Humane Society (in Missouri) - Iowa Transport

11101 University Ave Ste B, Clive, IA 50325

Pet Types: cats, dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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