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Mastiff puppies and dogs in Iowa

Looking for a Mastiff puppy or dog in Iowa? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Iowa

Below are our newest added Mastiffs available for adoption in Iowa. To see more adoptable Mastiffs in Iowa, use the search tool below to enter specific criteria!
Photo of Takoda

Takoda

Mastiff/Mixed Breed (Medium)

Male, 4 yrs 2 mos
Council Bluffs, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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Photo of Huebert

Huebert

Mastiff/Mixed Breed (Medium)

Male, 5 yrs
Council Bluffs, IA
Size
(when grown) -
Details
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Story
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Photo of Siggy

Siggy

Mastiff/Great Pyrenees

Female, Adult
Des Moines, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained,
Story
Siggy is a stunning 2-year-old, 82-pound Mastiff/Great Pyrenees mix with a friendly and loving personality! She adores meeting new people and has been great with other dogs at the rescue.Originally found as a stray, Siggy was cared for by her finders for about six months before coming to us. She’s adjusting well and has already shown what a wonderful companion she is. She’s house trained, enjoys the water, and is ready to bring her sweet, gentle nature into a forever home.If you’re looking for a big, affectionate pup who will be your loyal best friend, Siggy is waiting to meet you!Let me know if you’d like any more tweaks!IMPORTANT: Please read all below, especially if you live outside of Texas, which is where our rescue is located.Apply to adopt on our website: https://www.charmingpetrescue.org/adoptAll of our animals are spayed/neutered, microchipped, and up to date on shots.ALL of our animals are located in Boerne, TX, but transport after adoption is available to other states for a $300 fee for dogs or an additional fee varying by location for cats. If you are seeing our pets posted in your state, that's because you live near a transport stop, they are not currently at that location. Petfinder lists our pets as 'Out of Town' pets at other locations, and Adopt-a-Pet lists our location as a Transport stop. Those are currently the only options they offer to make this clear, so we put this description we've put at the bottom to explain it. You can read more about transport here: www.charmingpetrescue.org/transportWe understand transport is not an option for everyone, but we offer it at the cost we pay the transport company for those who wish to adopt from us.April 9, 2025, 5:27 am
Photo of CHAP

CHAP

Mastiff

Male, 8 yrs 1 mo
Ames, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
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Photo of Khloe

Khloe

Mastiff

Female, Adult
Cedar Rapids, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Good with dogs, House-trained,
Story
You can fill out an adoption application online on our official website. Khloe is a 7 years young English Mastiff, aged to perfection who lost her family due to tragedy. She is INCREDIBLY smart and knows several commands, so we believe her previous family had put a lot of love and effort into this amazing girl. Khloe loves road trips and rides very well in vehicles. She also kennels like a pro! Khloe is excellent with the medium and large dogs in her foster home, plus she is also well socialized with humans. She has not lived with children before and sometimes doesn't realize her extra large size so a home without kids would be best! (Imagine 130 Ibs trying to crawl into your child's lap:)) Khloe is working on her manners but is best fed alone in her kennel only. We would love to see Khloe go to a home that is familiar with her breed or with owning an XL dog.  Khloe's adoption fee is $250 and includes her spay, microchip, current vaccinations, and preventatives plus a free basic training course. Khloe is seeking an indoor only home and Last Hope requires that all adopters have a history of keeping their animals altered and current on vaccinations/prevention. If you would like to meet or adopt Khloe, please submit an adoption application on our website Adopthope.org. Our adoption process includes a background check, vet history check, and a home visit.  Visit this organization's web site to see any additional information available about this pet.January 27, 2025, 3:27 pm
Photo of Evie (Courtesy Post)

Evie (Courtesy Post)

Mastiff

Female, 6 yrs 4 mos
Council Bluffs, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, House-trained,
Story
Meet Evie, a loving and loyal gal who is looking for her forever home (mixed Mastiff, born 12/2018). She has been rescued and rehomed a few times at no fault of her own - and she's ready to settle down and grow old with a forever family that is able to give her all the love she deserves. Evie loves kids, snuggles, and spending time outside. Not only is she a sweetie - she's a genius! Evie is leash-trained, kennel-trained, potty-trained, and knows basic commands (sit, stay, etc.) She needs a fenced yard with room to run around. Evid would do great in a home where she's the only pet and with someone who has plenty of love to share. Apply to adopt Evie today!  The suggested adoption donation for Evie is $375, which includes a lifetime of free relationship-based training for any behavioral problems (not obedience training). Muddy Paws is a 501c3 non-profit organization meaning that part of your donation MAY be TAX DEDUCTIBLE. We are a 100% volunteer rescue committed to giving animals a second chance at life. All donations go toward that mission. Adoption fees are the primary source of funding for the cost of veterinary care for our animals. In 2022 alone, we provided animal Healthcare totaling over $399,000 covered mainly through adoption fees. Please Note:  A Courtesy Post designates that an animal is still in the home of its owner and not in a Muddy Paws foster. This means that our exposure to the animal is limited since we only assist the owner in finding a new home for their pet. From time to time owner,s find a new furever home for their pets outside of Muddy Paws Last Chance Rescue, and there is a delay in removing them from our site. We apologize if the Courtesy Post you apply to adopt is unavailable for adoption. Information about the adoption process:  All adoptions require a completed ADOPTION APPLICATION. Once your application has completed our prescreen steps, we will put you in touch with the animal’s foster to see if you and the pet are a good match. If so, we will arrange a meeting for you and the animal. The adoptions for all of our animals will take place in the Omaha, NE area and must be done by the adoptive family in person. We do not ship or deliver. Please Note:  We are a RESCUE, which is different from a shelter. We conduct veterinary and personal reference checks, and a Home Visit (Virtual in some cases) during the application approval process. We always select the right applicant for each animal, based on the animal’s needs. If you and the animal are not a good match, we will help you select another animal, or we will keep your approved application on file for 6 months. To learn about Muddy Paws Last Chance Rescue or donate to our animals, please visit our website at MuddyPawsSecondChanceRescue.com or our Facebook Page Muddy Paws Second Chance Rescue Inc. ##2255529##

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Iowa.

Mastiff puppies and dogs in Iowa cities

Mastiff Puppies near me Mastiff in Adel Mastiff in Algona Mastiff in Altoona Mastiff in Ames Mastiff in Anamosa Mastiff in Ankeny Mastiff in Atlantic Mastiff in Bettendorf Mastiff in Boone Mastiff in Burlington Mastiff in Carroll Mastiff in Cedar Falls Mastiff in Cedar Rapids Mastiff in Centerville Mastiff in Chariton Mastiff in Charles City Mastiff in Cherokee Mastiff in Clarinda Mastiff in Clear Lake Mastiff in Clinton Mastiff in Clive Mastiff in Coralville Mastiff in Council Bluffs Mastiff in Creston Mastiff in Davenport Mastiff in Decorah Mastiff in Denison Mastiff in Des Moines Mastiff in De Witt Mastiff in Dubuque Mastiff in Eldridge Mastiff in Estherville Mastiff in Evansdale Mastiff in Fairfield Mastiff in Fort Dodge Mastiff in Fort Madison Mastiff in Glenwood Mastiff in Grimes Mastiff in Grinnell Mastiff in Harlan Mastiff in Hiawatha Mastiff in Independence Mastiff in Indianola Mastiff in Iowa City Mastiff in Iowa Falls Mastiff in Johnston Mastiff in Keokuk Mastiff in Knoxville Mastiff in Le Mars Mastiff in Manchester Mastiff in Maquoketa Mastiff in Marion Mastiff in Marshalltown Mastiff in Mason City Mastiff in Mount Pleasant Mastiff in Muscatine Mastiff in Nevada Mastiff in Newton Mastiff in North Liberty Mastiff in Norwalk Mastiff in Oelwein Mastiff in Orange City Mastiff in Osceola Mastiff in Oskaloosa Mastiff in Ottumwa Mastiff in Pella Mastiff in Perry Mastiff in Pleasant Hill Mastiff in Red Oak Mastiff in Sheldon Mastiff in Shenandoah Mastiff in Sioux Center Mastiff in Sioux City Mastiff in Spencer Mastiff in Spirit Lake Mastiff in Storm Lake Mastiff in Urbandale Mastiff in Vinton Mastiff in Washington Mastiff in Waterloo Mastiff in Waukee Mastiff in Waverly Mastiff in Webster City Mastiff in West Des Moines Mastiff in Windsor Heights Mastiff in Winterset

Mastiff shelters & rescues in Iowa

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Iowa. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Last Hope Animal Rescue

1825 16th Ave SW, Cedar Rapids , IA 52404

Pet Types: cats, dogs

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Shelter

Ames Animal Shelter

325 Billy Sunday Road, Ames , IA 50010

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

Charming Pet Rescue - IA Transport Stop

Des Moines , IA 50309

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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