Adopt
Rehome
Menu Hamburger Icon

Mastiff puppies and dogs in Des Moines, Iowa

Looking for a Mastiff puppy or dog in Des Moines, Iowa? Adopt a Pet can help you find an adorable Mastiff near you.

Picture of Mastiff

Learn More:

Adopt a Mastiff near you Mastiff in cities near Des Moines, Iowa Other pups in Des Moines, Iowa Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Des Moines, Iowa Mastiff shelters and rescues in Des Moines, Iowa Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Des Moines, Iowa

These Mastiffs are available in Des Moines, Iowa.
We'll also keep you updated on He-Man's adoption status with email updates.
Photo of He-Man

He-Man

Mastiff

Male, Puppy
Urbandale, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
Born March 2019 and was not neutered. He is a great guard dog and has been great with my 2yo and 3yo children their whole lives. He eats Purina One large breed dog food. He is hesitant and will bark at new people until you let him know they are ok. Tall men make him skittish until they sit and he can sniff them. He has never bitten anyone or anything but will bark if strangers make fast movements towards him. Basically a big lovable lap dog that is just 150 lbs. He is very protective also, so if someone grabs you aggressively he will knock them off you. Looking for a home that he will be loved and played with since he is active.

Learn More

Small right facing arrow

Or, how about these Mastiffs in cities near Des Moines, Iowa

These Mastiffs are available for adoption close to Des Moines, Iowa.
We'll also keep you updated on Aries's adoption status with email updates.
Photo of Aries

Aries

Mastiff Boxer

Female, 5 yrs 8 mos
West Des Moines, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Aries is a beautiful mastiff/ boxer mix with a big heart (and a big head). She loves her people and does great with other dogs. Her goofy grin melts the hearts of those around her and her somewhat shy yet playful demeanor is what always seals the deal on staff and volunteers. Everyone here has fallen in love with this big goofy girl and we are sure you will too!

Learn More

Small right facing arrow
We'll also keep you updated on Tank's adoption status with email updates.
Photo of Tank

Tank

Mastiff American Pit Bull Terrier

Male, 2 yrs 4 mos
Marshalltown, IA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
-
Story
Tank is a 2 year old English Mastiff. He is a big boy with lots of love to give. He enjoys playing fetch and being outside. Tank would like to reserve a spot on the couch for evening cuddles - since he thinks he`s a lap dog. Tank came to us through a bite case. He was involved in an altercation with another dog. He has done well with the dogs here, so if you have a current dog in the home, several meet and greets will be required to make sure everyone gets along. Tank`s adoption fee covers his neuter, vaccines, microchip, heartworm test and various other treatments. If you are interested in Tank, please stop by the front desk or call 641-753-9046.

Learn More

Small right facing arrow

These pups are in Des Moines, Iowa too!

Below are our newest added Mastiffs available for adoption in Des Moines, Iowa. To see more adoptable Mastiffs in Des Moines, Iowa, use the search tool below to enter specific criteria!
We'll also keep you updated on Salus's adoption status with email updates.
Photo of Salus

Salus

St. Bernard Coonhound

Male, 4 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
We are about as adorable as it gets. We are a mix of St. Bernard/Aussie and Coonhound. We will be big, loveable family members. Won't you take one of us home with you? Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2196507##

Learn More

Small right facing arrow
We'll also keep you updated on Moko's adoption status with email updates.
Photo of Moko

Moko

St. Bernard Coonhound

Female, 4 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
We are about as adorable as it gets. We are a mix of St. Bernard/Aussie and Coonhound. We will be big, loveable family members. Won't you take one of us home with you? Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2196500##

Learn More

Small right facing arrow
We'll also keep you updated on Zita's adoption status with email updates.
Photo of Zita

Zita

St. Bernard Coonhound

Female, 4 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
We are about as adorable as it gets. We are a mix of St. Bernard/Aussie and Coonhound. We will be big, loveable family members. Won't you take one of us home with you? Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2196501##

Learn More

Small right facing arrow

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Des Moines, Iowa.

    an arrow icon
  • Columbus, OH
  • Columbus, OH
  • Columbus Grove, OH
  • Columbus Grv, OH

Sorry, we can’t find that location! Please try again.

    Age
    an arrow icon

Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Altoona, IA Mastiff in Ames, IA Mastiff in Ankeny, IA Mastiff in Boone, IA Mastiff in Clive, IA Mastiff in Grimes, IA Mastiff in Indianola, IA Mastiff in Johnston, IA Mastiff in Knoxville, IA Mastiff in Nevada, IA Mastiff in Newton, IA Mastiff in Norwalk, IA Mastiff in Perry, IA Mastiff in Pleasant Hill, IA Mastiff in Urbandale, IA Mastiff in Waukee, IA Mastiff in West Des Moines, IA

Related breeds in Des Moines, Iowa

Bullmastiffs in Des Moines, Iowa Neapolitan Mastiffs in Des Moines, Iowa Saint Bernards in Des Moines, Iowa

Mastiff shelters & rescues in Des Moines, Iowa

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Des Moines, Iowa. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

6.6 miles

Furry Friends Refuge

1211 Grand Ave, West Des Moines, IA 50265

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

More an arrow icon

Shelter

47.4 miles

Animal Rescue League of Marshalltown

1921 Taylor Avenue, Marshalltown, IA 50158

Pet Types: cats, birds, dogs, rabbits, small animals

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

clipboard with list

Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

Learn More an arrow icon