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Mastiff puppies and dogs in Millersville, Pennsylvania

Looking for a Mastiff puppy or dog in Millersville, Pennsylvania? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Millersville, Pennsylvania

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Or, how about these Mastiffs in cities near Millersville, Pennsylvania

These Mastiffs are available for adoption close to Millersville, Pennsylvania.
We'll also keep you updated on Xena's adoption status with email updates.
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Xena

Mastiff

Female, Young
Marietta, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Xena is a wonderful, gentle dog with a sweet and loving personality. She is amazing with children and enjoys being around people. At 4 years old, she has a calm nature, she likes short walks and is perfectly happy spending most of her day relaxing and napping. Xena loves attention, especially being pet, and is a big fan of snuggling up with her humans. She would make a loyal and affectionate companion in a loving home.
We'll also keep you updated on Bruno PPJ's adoption status with email updates.
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Bruno PPJ

Mastiff

Male, Young
York transport, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.Thank you for checking out our wonderful orphans. If you would like to find out more please email or call Diane at...diane@ulpr.org or 870-577-3744.   Please email us at  diane@ulpr.org  and request an application.Visit this organization's web site to see any additional information available about this pet.March 15, 2026, 12:14 am
We'll also keep you updated on Howie's adoption status with email updates.
Photo of Howie

Howie

Mastiff Mixed Breed (Medium)

Male, 8 mos
Manchester, PA
Size
(when grown) -
Details
-
Story
-
We'll also keep you updated on Blake's adoption status with email updates.
Photo of Blake

Blake

Mastiff Mixed Breed (Medium)

Male, 8 mos
Manchester, PA
Size
(when grown) -
Details
-
Story
Blake is a Cane Corso puppy we’re already completely smitten with. He’s a handsome little hunk of contradictions—equal parts lazy cuddle bug and playful goofball. Most of the time he’s quiet and laid-back, happily chewing away or lounging nearby, but he’ll find his voice when he thinks something needs to be “handled” (like eagles overhead or mysterious outside noises). Personal space? Not in Blake’s vocabulary. He’s happiest snuggled up as either the big spoon or the little spoon, and he has a special talent for waking you up with gentle face boops and slightly scratchy kisses. Coming from a home with lots of dogs, Blake is very in tune with canine communication. He reads other dogs well and responds beautifully to their cues. He’s much more relaxed and happy with a dog companion around and would love a playful fur sibling, though he’d also be content with a calmer, older dog friend. He’s also currently living in a home with chickens and has been doing well learning to coexist with them under supervision. Blake is still learning about the world and hasn’t had much socialization yet, so his future family will need to continue showing him that new experiences are safe and fun. The good news is he’s been handling everything so far with curiosity and resilience, without any signs of fear-based aggression. He’s house trained, knows “sit,” and takes treats ever so gently. Crate training is coming along nicely, and he’s eager to learn more. Blake truly wants to please and thrives on being close to his people. All in all, he’s a sweet, sensitive, and loyal pup who’s going to make an incredible companion for the right home.
We'll also keep you updated on Johnny's adoption status with email updates.
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Photo of Johnny

Johnny

Mastiff Great Dane

Male, Adult
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE NOTE! Unless stated otherwise, our dogs and puppies are located in Arkansas, and transported to the north/northeast once adopted. We do occasionally have dogs/puppies placed in foster homes in the north/northeast. In the cases where the pet is somewhere other than Arkansas, it will be noted beside the name of the pet.3/28/26 Located in NY! Johnny is looking for his forever home!!  Where are my mastiff lovers? This big boy was adopted from me in January but the adoption just isnt working out. I believe he needs a lot more exercise than he is getting. He is a sweet big baby that would benefit from a strong leader and some training. While here in Arkansas he did fantastic in a daycare setting with many other dogs. He is a young adult, approx 2 years old, and weighs just over 100 lbs. He is currently located in New York. Please email us with any questions.  apps.aasr@gmail.com To apply to adopt: https://form.jotform.com/212690945239059Visit this organization's web site to see any additional information available about this pet.Our typical adoption fee for puppies younger than 6 months old is $400, and for older puppies and adults, the usual fee is $350. This includes microchip, spay/neuter,  up to date on age appropriate vaccinations, dewormings, flea/tick treatment, and heartworm test (if over 6 months old) as well as heartworm treatment if they test positive. There is a transport fee of $150 per dog, depending on the transporter. We use Pack Leaders Rescue Dog Transport most often, but also use Hearts Transport as well on occasion. Please visit our Facebook page too! https://www.facebook.com/adoptastrayrescueorg For more info regarding adopting, email apps.aasr@gmail.com Thank you for considering one of our rescue babies!March 29, 2026, 11:10 am
We'll also keep you updated on Fernie *Courtesy Post*'s adoption status with email updates.
Photo of Fernie *Courtesy Post*

Fernie *Courtesy Post*

Mastiff

Female, Young
Harrisburg, PA
Size
(when grown) -
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Fern is now available please read her PetFinder post  https://www.petfinder.com/dog/fernie-d98ba9c5-c010-4bc0-b0e0-0e56e047e84b/pa/warrington/brookline-labrador-rescue-pa06/details/Click here to watch a video of Fernie *Courtesy Post*.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. &#226&#128&#139Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   March 7, 2026, 8:16 pm

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Mastiff shelters & rescues in Millersville, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Millersville, Pennsylvania. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

18.9 miles

Pitter Pat Junction, York PA transport

York transport, PA 17403

Pet Types: dogs

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Rescue

20 miles

Koch's Corsos & Rescues

Manchester, PA 17345

Pet Types: dogs

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Rescue

30.8 miles

Adopt A Stray - PA transport

Harrisburg, PA 17105

Pet Types: dogs

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Rescue

30.9 miles

Mastiffs To Mutts - Central PA

Harrisburg, PA 17109

Pet Types: dogs

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Shelter

32.8 miles

Waiting Under the Willow Foundation - PA Transport

Harrisburg, PA 17112

Pet Types: dogs

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Rescue

38 miles

Mastiffs to Mutts - Eastern PA

Exton, PA 19341

Pet Types: dogs

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Rescue

40.1 miles

Angel's Retreat

West Chester, PA 19382

Pet Types: dogs

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Rescue

43.8 miles

Pitter Pat Junction, MD transport

Towson transport, MD 21204

Pet Types: dogs

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Rescue

46.4 miles

God's Dog's Rescue of TX for MD Transport stop

Baltimore, MD 21212

Pet Types: dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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