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Mastiff puppies and dogs in Carlisle, Pennsylvania

Looking for a Mastiff puppy or dog in Carlisle, Pennsylvania? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Carlisle, Pennsylvania

These Mastiffs are available in Carlisle, Pennsylvania.
We'll also keep you updated on PUMPKIN's adoption status with email updates.
Photo of PUMPKIN

PUMPKIN

Mastiff

Female, Young
CARISLE, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PUMPKIN IS IN HER FOSTER HOME IN MEMPHIS, TN, AND WILL BE TRANSPORTED TO PA ONCE ADOPTED!    Pumpkin is a big, beautiful Mastiff mix who is about one year old and weighs around 115 pounds. She’s a loving, playful girl who enjoys treats and spending time outside. Pumpkin can be a little shy at first, so her adopters will need to be patient and give her time to feel comfortable. Once she warms up, she’s incredibly sweet and affectionate. She is crate trained and housebroken, and she walks well on a leash. Pumpkin enjoys walks around the neighborhood and trips to the park. After a day of fun, she’s happiest snuggling on the couch with her people. Despite her big size, Pumpkin is calm, quiet, and gentle — the perfect companion for someone looking for a loyal and loving friend. She is fully vetted. Vetting includes spay/neuter, microchip, rabies and all dog vaccinations. Her adoption fee of $600 includes the transport to PA. We use a licensed and registered USDA transport company that will bring Pumpkin up north to her new family. You can apply to adopt her today!     If you have any questions, please email us at: newbeginnings_animalrescue@yahoo.com   You can apply to adopt Pumpkin here: www.newbeginningsanimalrescue.net   THANK YOU FOR CONSIDERING ADOPTING A RESCUED PET! Visit this organization's web site to see any additional information available about this pet.March 7, 2026, 5:39 pm

Or, how about these Mastiffs in cities near Carlisle, Pennsylvania

These Mastiffs are available for adoption close to Carlisle, Pennsylvania.
We'll also keep you updated on PUMPKIN's adoption status with email updates.
Photo of PUMPKIN

PUMPKIN

Mastiff

Female, Young
CARISLE, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PUMPKIN IS IN HER FOSTER HOME IN MEMPHIS, TN, AND WILL BE TRANSPORTED TO PA ONCE ADOPTED!    Pumpkin is a big, beautiful Mastiff mix who is about one year old and weighs around 115 pounds. She’s a loving, playful girl who enjoys treats and spending time outside. Pumpkin can be a little shy at first, so her adopters will need to be patient and give her time to feel comfortable. Once she warms up, she’s incredibly sweet and affectionate. She is crate trained and housebroken, and she walks well on a leash. Pumpkin enjoys walks around the neighborhood and trips to the park. After a day of fun, she’s happiest snuggling on the couch with her people. Despite her big size, Pumpkin is calm, quiet, and gentle — the perfect companion for someone looking for a loyal and loving friend. She is fully vetted. Vetting includes spay/neuter, microchip, rabies and all dog vaccinations. Her adoption fee of $600 includes the transport to PA. We use a licensed and registered USDA transport company that will bring Pumpkin up north to her new family. You can apply to adopt her today!     If you have any questions, please email us at: newbeginnings_animalrescue@yahoo.com   You can apply to adopt Pumpkin here: www.newbeginningsanimalrescue.net   THANK YOU FOR CONSIDERING ADOPTING A RESCUED PET! Visit this organization's web site to see any additional information available about this pet.March 7, 2026, 5:39 pm
We'll also keep you updated on Johnny's adoption status with email updates.
Photo of Johnny

Johnny

Mastiff Great Dane

Male, Adult
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE NOTE! Unless stated otherwise, our dogs and puppies are located in Arkansas, and transported to the north/northeast once adopted. We do occasionally have dogs/puppies placed in foster homes in the north/northeast. In the cases where the pet is somewhere other than Arkansas, it will be noted beside the name of the pet.3/28/26 Located in NY! Johnny is looking for his forever home!!  Where are my mastiff lovers? This big boy was adopted from me in January but the adoption just isnt working out. I believe he needs a lot more exercise than he is getting. He is a sweet big baby that would benefit from a strong leader and some training. While here in Arkansas he did fantastic in a daycare setting with many other dogs. He is a young adult, approx 2 years old, and weighs just over 100 lbs. He is currently located in New York. Please email us with any questions.  apps.aasr@gmail.com To apply to adopt: https://form.jotform.com/212690945239059Visit this organization's web site to see any additional information available about this pet.Our typical adoption fee for puppies younger than 6 months old is $400, and for older puppies and adults, the usual fee is $350. This includes microchip, spay/neuter,  up to date on age appropriate vaccinations, dewormings, flea/tick treatment, and heartworm test (if over 6 months old) as well as heartworm treatment if they test positive. There is a transport fee of $150 per dog, depending on the transporter. We use Pack Leaders Rescue Dog Transport most often, but also use Hearts Transport as well on occasion. Please visit our Facebook page too! https://www.facebook.com/adoptastrayrescueorg For more info regarding adopting, email apps.aasr@gmail.com Thank you for considering one of our rescue babies!March 30, 2026, 6:42 pm
We'll also keep you updated on Fernie *Courtesy Post*'s adoption status with email updates.
Photo of Fernie *Courtesy Post*

Fernie *Courtesy Post*

Mastiff

Female, Young
Harrisburg, PA
Size
(when grown) -
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Fern is now available please read her PetFinder post  https://www.petfinder.com/dog/fernie-d98ba9c5-c010-4bc0-b0e0-0e56e047e84b/pa/warrington/brookline-labrador-rescue-pa06/details/Click here to watch a video of Fernie *Courtesy Post*.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. &#226&#128&#139Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   March 7, 2026, 8:16 pm
We'll also keep you updated on Rufio's adoption status with email updates.
Photo of Rufio

Rufio

Mastiff

Male, 6 yrs 8 mos
Harrisburg, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Rufio is a gentle soul. He is a little shy and more on the quiet side. He does good with other dogs, even small ones.I just can’t say enough sweet things about this pup. He is good in a car and is learning the leash. It takes a little while for him to trust new people, but once he does, his goofy and sweet personality shines!Rufio is medium energy and would do great with any family with a little patience. Rufio is not completely potty trained. He still marks in the house but is working on that.Located in Houston, Tx. Transport to most states available for an additional fee of $300.
We'll also keep you updated on Mia Female 2's adoption status with email updates.
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Photo of Mia Female 2

Mia Female 2

Mastiff

Female, 1 mo
Manchester, PA
Size
(when grown) Small 25 lbs (11 kg) or less
Details
-
Story
-
We'll also keep you updated on Baby Girl's adoption status with email updates.
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Photo of Baby Girl

Baby Girl

Mastiff

Female, 3 yrs 6 mos
Manchester, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Good with cats,
Story
Baby Girl — 3–4 Years Old | 95 lbs | Big Love, Bigger Personality Baby Girl is exactly what her name suggests—a giant sweetheart who believes the world is full of friends she just hasn’t met yet. Found as a stray alongside a French Bulldog, she’s proven to be resilient, loving, and ready to settle into a home of her own. Weighing in at 95 pounds, Baby Girl brings plenty of presence—and plenty of slobber to match! She’s strong on leash and will need someone ready to work on her manners, but she makes up for it with her affectionate nature and eagerness to connect. She’s a social butterfly with no stranger danger, happily greeting new people like long-lost friends. While she hasn’t been kid-tested yet, she does well with cats and other dogs, making her a great candidate for a multi-pet household. At home, Baby Girl is full of personality: She knows how to sit and politely waits for permission before eating She’ll “tell” you when she needs something—with a whine that could mean potty, hunger, or bedtime She keeps a strict bedtime of 8:30–9:00 PM (and expects you to respect it!) She politely asks before hopping into bed She loves her toys… and will scatter them everywhere like adorable little booby traps Baby Girl has not yet been vetted or spayed, but updates are coming soon. If you’re looking for a big, goofy, loving companion who will keep you on a schedule and fill your home with laughter (and a little drool), Baby Girl might just be your perfect match.

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Mastiff shelters & rescues in Carlisle, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Carlisle, Pennsylvania. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

6.5 miles

New Beginnings Animal Rescue - Carisle, PA Transport

CARISLE, PA 17013

Pet Types: cats, dogs

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Rescue

21.6 miles

Adopt A Stray - PA transport

Harrisburg, PA 17105

Pet Types: dogs

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Rescue

21.6 miles

Mastiffs To Mutts - Central PA

Harrisburg, PA 17109

Pet Types: dogs

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Shelter

22.4 miles

Waiting Under the Willow Foundation - PA Transport

Harrisburg, PA 17112

Pet Types: dogs

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Rescue

25.5 miles

Koch's Corsos & Rescues

Manchester, PA 17345

Pet Types: dogs

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Rescue

30.3 miles

Pitter Pat Junction, York PA transport

York transport, PA 17403

Pet Types: dogs

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Rescue

48.2 miles

Focus on Cumberland County Animal Safety - MD transport stop

Hagerstown, MD 21740

Pet Types: cats, dogs

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Rescue

48.2 miles

Lucky's Legacy Rescue

Hagerstown, MD 21740

Pet Types: cats, dogs, reptiles, small animals

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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