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Mastiff puppies and dogs in Des Peres, Missouri

Looking for a Mastiff puppy or dog in Des Peres, Missouri? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Des Peres, Missouri Other pups in Des Peres, Missouri Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Des Peres, Missouri Mastiff shelters and rescues in Des Peres, Missouri Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Des Peres, Missouri

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Des Peres, Missouri

These Mastiffs are available for adoption close to Des Peres, Missouri.
We'll also keep you updated on Rosie's adoption status with email updates.
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Rosie

Mastiff

Female, Young
Webster Groves, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Rosie was found tied to post behind an abandoned building. Suspected to be used in dog fighting. I fell in love with her the moment I met her. Brought my son and my dog to meet her and they all got along great. However, Rosie began to attach herself to me and attacked our dog twice, but gets along fine with my boyfriends dog - they play a lot! She has snarled at son. We have been working on her reactivity. However, I am nervous with her around my son. She is so sweet and cuddly - she thinks she is a lap dog. However, she will defend no matter what and this makes me very nervous. We are starting muzzle training but she can’t be in a muzzle 24/7 and I’m nervous about her snarling at my son. She is great with cats needs- I think ideally she would be in a quiet home with no other dogs (tho would probably enjoy play with a muzzle on) and probably no kids. She is on high alert and very guarding of her people - she love her people so so much

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We'll also keep you updated on Valentino's adoption status with email updates.
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Valentino

Mastiff Labrador Retriever

Male, 6 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Are you looking for a life-long love? I'm sure to make your heart skip a beat with these longing eyes! Hey there, I'm Valentino! I've had a rough start in life as my owners moved and decided to leave my brother and I behind. We don't let it bother us as we know we will find our forever homes soon. We look to be a mix of Mastiff/Lab but the shelter isn't sure. Will you paw-lease adopt me?  If you're interested in adopting me, fill out an adoption application online at www.polkcountyhumanesociety.org/adopt where you will also find a link to reserve me for an appointment. Some pets are in foster homes or may already have an appointment scheduled, so the appointment is important to make sure I will be available to meet you when you come. Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2287925##

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We'll also keep you updated on Romeo's adoption status with email updates.
Photo of Romeo

Romeo

Mastiff Labrador Retriever

Male, 6 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Are you looking for a life-long love? I'm sure to make your heart skip a beat with these longing eyes! Hey there, I'm Romeo! I've had a rough start in life as my owners moved and decided to leave my brother and I behind. We don't let it bother us as we know we will find our forever homes soon. We look to be a mix of Mastiff/Lab but the shelter isn't sure. Will you paw-lease adopt me?  If you're interested in adopting me, fill out an adoption application online at www.polkcountyhumanesociety.org/adopt where you will also find a link to reserve me for an appointment. Some pets are in foster homes or may already have an appointment scheduled, so the appointment is important to make sure I will be available to meet you when you come. Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2287932##

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We'll also keep you updated on Serena's adoption status with email updates.
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Serena

Mastiff

Female, Puppy
Fenton, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats,
Story
Serena(Williams) was born on 11/17/24. She is going to be a good sized girl considering her dad is a mastiff mix, and momma is a country mutt! She LOVES to play! She would love to have another playful pup in the house! She is getting spayed on 2/4, but can be spoken for before then.January 22, 2025, 12:50 pm

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We'll also keep you updated on Shaq's adoption status with email updates.
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Shaq

Mastiff

Male, Puppy
Fenton, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats,
Story
Shaq(O’Neal) was born on 11/17/24. His dad is a mastiff mix, and mom is a country mutt. He will be a good sized boy! He absolutely LOVES to play with his sister, so it would be great if he could have another playful pup friend in his new home. He is getting neutered on 2/4, but can be spoken for before then. January 22, 2025, 1:12 pm

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We'll also keep you updated on Bellatrix aka "Willow Eliza"'s adoption status with email updates.
Photo of Bellatrix aka "Willow Eliza"

Bellatrix aka "Willow Eliza"

Mastiff

Female, 7 yrs 2 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Bella is big and beautiful with a personality to match. This six-year-old mastiff mix girl adores people, snuggles, pets, and attention. She is spayed and up-to-date on all her medical care and is heartworm-negative. Bella is a big girl, approximately 65 pounds, so while she is very good with people, she would be best with older kids who can keep up with her size. She is house-trained, and a fenced yard would be best since Bella is a large dog and likes to play. Bella likes her people so much she doesn't want to share and would do best as the only dog in her home. To meet Bella, visit istodaymydayrescue.org to fill out an application. Her adoption fee is $100.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Des Peres, Missouri

Bullmastiffs in Des Peres, Missouri Neapolitan Mastiffs in Des Peres, Missouri Saint Bernards in Des Peres, Missouri

Mastiff shelters & rescues in Des Peres, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Des Peres, Missouri. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

5.6 miles

Polk County Humane Society - St. Louis Transport

10900 Sunset Hills Plaza, St. Louis, MO 63127

Pet Types: cats, dogs

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Rescue

8 miles

4 Paws 4 Rescue

Fenton, MO 63026

Pet Types: cats, dogs, rabbits, small animals

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Rescue

8.4 miles

Is Today My Day Rescue

St. Louis, MO 63139

Pet Types: dogs

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Rescue

10.6 miles

Charming Pet Rescue - MO Transport Stop

St. Louis, MO 63303

Pet Types: dogs

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Rescue

12.1 miles

Nala and Friends Dog Rescue - ST. LOUIS transport

St. Louis, MO 63118

Pet Types: dogs

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Shelter

12.6 miles

CARE STL

2700 Walnut Place, St. Louis, MO 63103

Pet Types: cats, birds, dogs, farm animals, rabbits, small animals

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Shelter

14.8 miles

St Charles County Humane Services

4850 Mid Rivers Mall Dr, St. Peters, MO 63376

Pet Types: cats, birds, dogs, rabbits, small animals

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Rescue

14.8 miles

Stray Paws Rescue

7055 Mexico Rd., Box 1663, St. Peters, MO 63376

Pet Types: cats, dogs

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Shelter

24.6 miles

Belleville Area Humane Society

1301 S. 11th St., Belleville, IL 62223

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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