Mastiff Adoption in San Jose, CA: Mastiff Puppies for Sale in San Jose, CA

Adopt a Mastiff near you in San Jose, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near San Jose, California

These Mastiffs are available for adoption close to San Jose, California.

Rosco

Mastiff

Male, Young

Sunnyvale, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Rosco is a loving, affectionate dog looking for his perfect forever home. I adopted him from the San Jose Animal Center about two years ago when he was just 6 months old, and he’s now around 2–3 years old. Unfortunately, I don’t have the time or resources to give him the attention and training he deserves, so I’m hoping to find someone who can. Rosco is a gentle, clumsy giant with a heart of gold. He’s very sweet and docile and loves being close to his people. Rosco is crate trained and knows several commands, including sit, down, place, stay, and go eat. He would thrive in a home with a yard or outdoor space where he can stretch his legs and go to the bathroom easily. I’ll include his crate if needed.

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Dozer

Mastiff

Male, Adult

San jose, CA

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Spayed or Neutered, Shots are up-to-date,

Story

Dozer is a neutered male, black/white Mastiff Hi! I'm Dozer! I am deaf! I really don't know how to play. It’s kind of sad. I have a little routine here - I just go in my pen, eat a few bites, drink then run back out for a treat. I like being near my people & will follow you around. I am not interested in playing ball. I really just don't know what to do with myself other than just enjoy life. I am so sweet, according to my foster. So if you don't mind a good-sized velcro dog, I'm your guy! ##2498995##

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Romeo

Mastiff

Male, 6 yrs 8 mos

Palo Alto, CA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Not good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Romeo is very sweet 6 year old boy but the vets think he may be younger. He would love to be a family dog and definitely wants to find his forever home, but can be protective of his people and his space. That being said once he knows you are part of the family he listens very well and knows many commands, sit, stay, down, shake, wait. He is slow to warm up to new people but once he has been introduced to you he is a gentle giant and big couch potato that loves to cuddle. He also really enjoys going for a ride in the car. It is not recommended to have young kids due to his size. He is good on the leash and knows many commands but needs someone that is not afraid of his size and can properly handle him. Experienced adopter with larger breeds is a must. No other dogs or animals in the household and not a good candidate for crates.

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She-Ra - ECAS

Mastiff Mixed Breed (Medium)

Female, 5 yrs

Pleasanton, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

She-Ra was brought to our shelter on 11/17/25 after being found in unincorporated Livermore. She hasn't been reclaimed by her previous person, so she's now looking for a new home! Her adoption fee is $35, plus licensing (if applicable), plus the cost of her spay surgery. ☃️ Her adoption fee is waived this month, and her spay surgery has been sponsored! Licensing fee may still apply. 🎁 She-Ra’s Shelter ID# is 88279. She is an approximately 5-year-old, black, Mastiff mix. She currently weighs around 93 lbs. She has already been vaccinated and will be spayed and microchipped before going to her new home. She-Ra is located in kennel C-2. ** Age shown is an estimate only ** THIS IS A COURTESY POSTING If you are interested, please call the East County Animal Shelter at 925-803-7040 to see if this dog is still available.

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Rex

Mastiff Mixed Breed (Large)

Male, 1 yr 10 mos

Pleasanton, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

Meet Rex, our 98-lb gentle giant with a heart just as big as his blocky head. This stunning red Mastiff mix, just under 2 years old and already neutered, is the total package he is calm, polite, intelligent, and just the right amount of goofy. ✨ Why Rex is amazing: • Walks beautifully on leash • Knows “sit” and takes treats with a soft, gentle mouth • Affectionate once he warms up • Loves walks, lounging, and hanging with his people • May be cat workable with slow and proper intros 🐱❤️ In playgroups, Rex enjoys gentle play with both male and female dogs who don’t mind his big-dog enthusiasm. He thrives in a calm, structured home without too much chaos just a loving person or family who sees what a treasure he is. Neutered| 2 yrs old | 98 lbs | Mastiff Mix

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May May - ECAS

Mastiff Mixed Breed (Medium)

Female, 6 yrs

Pleasanton, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

May May was brought to our shelter on 11/22/25 after being found in Castro Valley. She hasn't been reclaimed by her previous person, so she's now looking for a new home! Her adoption fee is $35, plus licensing (if applicable). The cost of her spay surgery is sponsored! ☃️ Her adoption fee is waived this month, but adopter is responsible for the cost of her spay surgery. Licensing fee may still apply. 🎁 ## See video of May May at the end of the photo gallery! ## TVAR.org/find-your-pet-adopt/dogs-puppies/ May May’s Shelter ID# is 88332. She is an approximately 6-year-old, black, Mastiff mix. She currently weighs around 80 lbs. She has already been vaccinated and microchipped and will be spayed before going to her new home. May May is located in kennel B-5 ** Age shown is an estimate only ** THIS IS A COURTESY POSTING If you are interested, please call the East County Animal Shelter at 925-803-7040 to see if this dog is still available.

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Mastiff puppies and dogs in San Jose, California

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Mastiff puppies and dogs in San Jose, California

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Adopt a Mastiff near you in San Jose, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near San Jose, California

These Mastiffs are available for adoption close to San Jose, California.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in San Jose, California

Mastiff shelters & rescues in San Jose, California

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics