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Mastiff puppies and dogs in Poway, California

Looking for a Mastiff puppy or dog in Poway, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Poway, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Poway, California

These Mastiffs are available for adoption close to Poway, California.
Photo of Kali

Kali

Mastiff

Female, 5 yrs 9 mos
Ramona, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
*This is a courtesy listing.* Meet Kali! 5-year-old Kali needs a loving new home following the recent passing of her mom. Kali can be reserved when first meeting someone nd takes a bit to warm up, but she is very warm and affectionate when she gains trust in the person. Kali was very loving and devoted to her mom, and with time, she will share her big heart with a new family. She enjoys playing fetch and is good with the 2-year-old granddaughter of her late owner. For the past 5 years, Kali has lived with another dog (Kara, also available for adoption), and they get along very well. They eat alongside each other without issue and share space & attention nicely. Both dogs earn high marks from the care staff where they board. If you are looking for a loving, devoted, and well-behaved companion, Kali may be the one for you! To learn more, please email Sandra at sandraj111207@gmail.com. *Frosted Faces Foundation has not assessed this dog medically or behaviorally.*
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Photo of Milki

Milki

Mastiff Boxer

Female, Young
Escondido, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived: Milki was brought in by our Humane Law Enforcement team on 2/19/2025. Why this pet is the one for you:Meet Milki, a sweet and slightly shy girl looking for a loving home! She may take a little time to warm up, but once she does, she's all about cuddles and affection. Milki will thrive in a calm and patient environment, where she can feel safe and build trust. If you're ready to offer this gentle girl a peaceful space, she'll repay you with endless love and loyalty. Could Milki be the perfect addition to your family? Come visit her at our Escondido campus! At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for her new home! Primary Color: Fawn Secondary Color: Black Weight: 87.4 Age: 1yrs 0mths 0wks
Photo of Jacques-Merced, CA

Jacques-Merced, CA

Mastiff

Male, 1 yr 3 mos
Southern CA, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Location: Merced, CA Handsome hunky boy Jacques is around 11 months old. He was rescued off the streets by a kind elderly lady. No microchip or owner has been found. He is a big boy at 100 lbs and just a bit too much puppy for her to keep him. Jacques is sweet, friendly, a big lump of affection, super loving and great with the 4 yr. old child in the home. He loves car rides and playing in the yard chasing tennis balls. Chew bones are the bestest! He is partially blind in one eye but that doesn't stop him. He has been wonderful with the other dog & puppies that were also rescued off the streets, that are also with the elderly finder. Kitties are unknown. Jacques would make a wonderful addition to any family with his loving disposition. If you think he is the right one for you, reach out to the rescue: Copy & Paste the link below into your browser for our online application: https://www.jotform.com/form/243374218477059 Email us for any further questions: info@savethedals.org
Photo of Rex

Rex

Mastiff German Shepherd Dog

Male, Young
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by a community member on February 10, 2025. Why this pet is the one for you:Meet Rex! He is the definition of gentle giant. He has been quite timid with being in a shelter environment, but he loves pets and attention and will always want to be by your side. While we are still getting to know this pooch, we cannot deny one thing: they're ready for their next chapter in life! A consistent routine and fun, enriching activities will help them get used to their home and feel like part of the family! He has already been neutered, microchipped, and is up to date on all his vaccines. If you'd like to learn more about this pup come visit us at the San Diego Campus today! Primary Color: Brown Brindle Weight: 120 Age: 1yrs 3mths 1wks
Photo of Cuddles

Cuddles

Mastiff

Male, Adult
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by a community member on December 24, 2024. Why this pet is the one for you:Cuddles is a handsome, bashful guy looking for a chill household where he can blossom and show off his true colors. This wallflower does best with short interactions where he can take the lead. Once comfortable with you, there is no limit to the love yall can share! Cuddles will thrive in small household size with mature folks who can help build confidence. There's more that we're learning about this pup each day, and we can't wait to share more with you! Visit us today to adopt! Primary Color: Grey Secondary Color: Brindle Weight: 87.125 Age: 2yrs 1mths 4wks
Photo of Grizelda

Grizelda

Mastiff

Female, Adult
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by a community member on February 9, 2025. Why this pet is the one for you:Meet Grizelda! While we are still getting to know this pooch, we cannot deny one thing: they're ready for their next chapter in life! A consistent routine and fun, enriching activities will help them get used to their home and feel like part of the family! She has already been spayed, microchipped, and is up to date on all her vaccines. If you'd like to learn more about this pup come visit us at the San Diego Campus today! Primary Color: Tan Weight: 113 Age: 2yrs 0mths 1wks

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Mastiff shelters & rescues in Poway, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Poway, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

11.3 miles

Frosted Faces Foundation

1448 Pine St, Ramona, CA 92065

Pet Types: cats, dogs

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Shelter

12.5 miles

San Diego Humane Society - Escondido Campus

3500 Burnet Drive, Escondido, CA 92027

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

15.9 miles

Save the Dalmatians and Others Canine Rescue, Inc

San Diego, Orange County, Los Angeles, California, dogs are fostered in So California, Southern CA, CA 92104

Pet Types: dogs

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Shelter

16.3 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

20.4 miles

The Dank Dog Rescue & Sanctuary

Valley Center, CA 92082

Pet Types: dogs

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Rescue

21.9 miles

Underdog Heroes

Riverside, CA 92058

Pet Types: dogs

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Shelter

48 miles

Coastal Animal Services Authority

221 Avenida Fabricante, San Clemente, CA 92672

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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