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Mastiff puppies and dogs in Oro Valley, Arizona

Looking for a Mastiff puppy or dog in Oro Valley, Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Oro Valley, Arizona Other pups in Oro Valley, Arizona Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Oro Valley, Arizona Mastiff shelters and rescues in Oro Valley, Arizona Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Oro Valley, Arizona

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Oro Valley, Arizona

These Mastiffs are available for adoption close to Oro Valley, Arizona.
We'll also keep you updated on TANK's adoption status with email updates.
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TANK

Mastiff

Male, 2 yrs 9 mos
Tucson, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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We'll also keep you updated on LURCH*'s adoption status with email updates.
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LURCH*

Mastiff Labrador Retriever

Male, 2 yrs 1 mo
Tucson, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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We'll also keep you updated on JENKINS*'s adoption status with email updates.
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JENKINS*

Mastiff

Male, 2 yrs 1 mo
Tucson, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
House-trained, Spayed or Neutered,
Story
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We'll also keep you updated on RUGER*'s adoption status with email updates.
Photo of RUGER*

RUGER*

Mastiff

Male, 1 yr 1 mo
Tucson, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
If you’re looking for a sweet-as-pie, wrinkly-faced young pup with years of love to give and a heart of gold, look no further than Ruger! Ruger is a boy who loves his people and shelter pals and can’t wait to get into a home where he can spend lots of time with his furever family. He doesn’t care what you’re doing, as long as you’re together! Volunteers adore this boy, sharing:“Ruger was very polite greeting me in his kennel. He was easy to leash and excited to get out on his walk. He is extremely treat motivated and knows his sit command and he did well learning the “down” command. We walked all around the lake. He’s very affectionate and leans to you for a good side rub. He generally just likes affection. He likes to take his time on walks and take in the world. Overall, just a great guy.”Ruger is a smart and athletic dog who would love to find a family committed to giving him lots of physical and mental stimulation. He’s been working on crate training while in the shelter and this will be a crucial part of his success in a future home. Ruger would like to meet any potential furry housemates before heading to his furever home to ensure a good fit. If you’ve had your eyes peeled for a dog who’s as smart as he is handsome, look no further than very good boy Ruger!

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We'll also keep you updated on MOUSSE's adoption status with email updates.
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MOUSSE

Mastiff Chow Chow

Male, 2 yrs 7 mos
Tucson, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
EMERGENCY PLACEMENT DEADLINE5PM MONDAY 09/08/25AVAILABLE FOR ADOPTION ONLY THROUGH PACC Name: MousseAnimal ID: A869969Age: 2 yearsWeight: 88lbs.Web Link: 24petconnect.com/PimaAdoptablePets/Details/PIMA/A869969 About: Just like the delicious dessert he`s named after, our Mousse is a truly sweet guy. This dashing, robust, caramel-colored mixed breed is looking for a hero to give him his second chance at a forever home. Mousse has been through a lot in his young life and recently found himself back at the shelter, but we`re committed to helping him find his perfect fit.Mousse was originally found as a stray and was later adopted. Unfortunately, he was recently returned to the shelter. While we knew he had a history of resource guarding with other dogs, it was discovered in his adoptive home that he also struggles with resource guarding around children. Because of this, it is crucial that his new home has no children.Mousse also needs to be the only pet in the home. He has a history of resource guarding with other dogs, which led to a previous altercation and injury. It is essential that his new family fully understands this behavior and is prepared to take all necessary precautions to keep Mousse and any other household members safe.In his previous home, Mousse was described as a playful and affectionate dog who loved to be by his person`s side. His foster parent shared that Mousse has `so much love to give in the right home.` He`s a big boy with an even bigger heart; just waiting for a family to shower him with affection and provide the dedicated guidance he needs. He is energetic and will need a secure yard and monitoring to ensure he doesn`t attempt another escape.Mousse is a good dog who needs a savvy adopter who understands his unique needs. If you`re looking for a loyal, lifelong companion and believe your home is the perfect fit for Mousse to thrive, please come to PACC and ask to meet this magnificent boy. This is his last chance at finding his forever home, and he deserves a hero of his own.Available adoption Only through PACC.Interested parties:Must visit PACC before the 5:00PM Monday September 8, 2025 deadline to meet with a counselor who will review notes and introduce you to the dog to ensure that it’s a good fit. Some dogs may also require an introduction to any dogs they may potentially live with. Home Management PlanInjured Another Animal • alter

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We'll also keep you updated on MISO*'s adoption status with email updates.
Photo of MISO*

MISO*

Mastiff

Male, 6 yrs 4 mos
Tucson, AZ
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
House-trained, Spayed or Neutered,
Story
If you need to add some flavor to your life, we`ve got a quick and easy way to do that- meet Miso! Miso is a handsome young guy who first popped up at PACC all the way back in 2021. We don’t know all of the details of his journey between then and now, but he returned to the shelter as a stray in late 2024. Miso found himself at risk due to critical shelter overcrowding and was lucky enough to spend a couple of months in a foster home. Here’s what we learned:- He is housebroken and easily learned to use a doggy door- He slept the day away when left home alone- He is extremely cuddly and affectionate - He is calm and well- mannered- He is friendly with new people“Miso CLEARLY identifies as a 5lb teacup poodle. He wants nothing more than to crawl into your lap to be close to you. This doesn’t work out so well due to his size, but he works with the hand he was dealt and is content to get his paws and head in your lap. I can confirm he is redirectable if you don’t want his front half in your lap. He is a champion car passenger. He will stay in the backseat if that’s where you put him, but if you let him ride in the passenger seat, he will just lay there with his head in your lap.”Miso’s foster said that he was “one of the best dogs I’ve ever had in my home” and we’re hoping that when Miso leaves the shelter next, it will be forever this time!This big old lovebug also has lots of fans at the shelter- here’s what one of them had to say:“Miso is the biggest cuddle bug! He`d rather sit on your lap in a yard than to walk. His beautiful coat is fluffy and that makes petting fun. Miso is friendly and easy to leash.”Miso is a big, energetic boy so would love a family who will take him on all of their adventures. When meeting other dogs in playgroup Miso has been independent and more people- oriented than doggy social. He’d like to meet any resident dogs before heading home to ensure a good fit. Ask to meet Miso today!!

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Oro Valley, Arizona.

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Mastiff puppies and dogs in nearby cities

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Mastiff shelters & rescues in Oro Valley, Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Oro Valley, Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

14.1 miles

Pima Animal Care Center

4000 N. Silverbell Road, Tucson, AZ 85745

Pet Types: cats, dogs, rabbits, small animals

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Shelter

14.3 miles

Paws Without Borders

4115 East Lester Street, Tucson, AZ 85712

Pet Types: dogs

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Rescue

36 miles

The Big Mutt Network Inc

10875 S GREAT HORNED OWL WAY, Vail, AZ 85641

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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