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Great Dane puppies and dogs in Missouri

Looking for a Great Dane puppy or dog in Missouri? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Missouri

Below are our newest added Great Danes available for adoption in Missouri. To see more adoptable Great Danes in Missouri, use the search tool below to enter specific criteria!
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Nova 32401

Great Dane

Female, Puppy
Joplin, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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Story
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Lilly

Great Dane/Mastiff

Female, Young
Lees Summit, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, Needs experienced adopter, House-trained,
Story
Her name is Lilly. She turned one in February. She loves getting attention She loves to run and play. She’s very curious about cats. She is a mix of great Dane mastiff cane Corso German Shepherd bloodhound. But overall has the personality of a Great Dane and the appearance. She is a very sweet dog!! We just are not the best home for her due to the hours we work she does not get enough time with us and that’s unfair for her! I really hope we can find a great home for her!!
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Charlee

Great Dane/Bullmastiff

Female, Adult
Ozark, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
We have had Charlee since she was a brand new puppy. She is 6 years old and loves to lay around and be lazy. She loves to go out and run for a few minutes but then is ready to lay back down again. She is house broken and does not require kenneling when gone for the day. She also does not require being leashed when going on walks. She is well behaved and loves to be loved. A new home with plenty of time to love on her and play with her would be perfect!
Photo of Blue

Blue

Great Dane

Male, Young
Boonville, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained,
Story
Bluey came to me from a home who rescued him and wasn’t fit for him to stay. I have had him for about a year, he is a super sweet giant and is a good listener, we just don’t have time for him as we continue to remodel our home.
Photo of Appa

Appa

Great Dane

Male, Adult
Lake Ozark, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Needs experienced adopter, House-trained,
Story
We rescued Appa from a neglect situation and have nursed him back to health and happiness! He’s just about the cuddliest dog I’ve ever seen and would thrive in a one dog household where he can soak up all the love he missed out on for the first three years of his life. He can be as active as a puppy or as laid back a senior, depending on the energy around him. He has been neutered and tacked and will come with an orthopedic bed, gentle lead head halter, his favorite toys, a slow feeder food bowl, and a full bag of Purina Pro Plan Large Breed chicken dog food.
Photo of Kevin

Kevin

Great Dane/Labrador Retriever

Male, 1 yr 3 mos
Crocker, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Contact SaveMeAdoptMe@gmail.com or text or leave a message at 573-512-2102 for an application. The adoption donation of $175.00 covers spay / neuter, vaccinations, microchip, deworming, and current monthly heartworm and flea and tick prevention. Bros Kevin and Andrew are wonderful, beautiful Greyhound or Black Labrador or Great Dane mixes, kind of lanky yet sturdy. They are about 60 lb and I would expect them to be 70 to 80 lb when full grown? I'm guessing them to have been born Feb 2024. They showed up on a property next to a busy, rural highway, so presume they were dumped. They are wonderful in the house with full-time doggie door access so they can go potty when needed. If no doggie door they would need time to adjust to a schedule and learn to ask to go out. They sleep in a crate at night. They still have puppy energy and really enjoy playing, especially with each other but seem like they will be relatively calm dogs. They love to snuggle and also for you to lay on the floor with them. They are very bonded, so if you happen to want 2 beautiful additions they would be great together.

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Missouri.

Great Dane puppies and dogs in Missouri cities

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Great Dane shelters & rescues in Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Missouri. Browse these Great Dane rescues and shelters below.

Here are a few organizations

Shelter

Polk County Humane Society - St. Louis Transport

10900 Sunset Hills Plaza, St. Louis , MO 63127

Pet Types: cats, dogs

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Shelter

Five Acres Animal Shelter

1099 Pralle Lane, St. Charles , MO 63303

Pet Types: cats, dogs

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Rescue

All About Paws

Po Box 621, Bridgeton , MO 63044

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog ?

We've got all the info you need on adopting and caring for a Great Dane puppy . Check out the links below for everything you ever wanted to know about Great Dane puppies and adults .

Great Dane information

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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