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Great Dane puppies and dogs in San Diego, California

Looking for a Great Dane puppy or dog in San Diego, California? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in San Diego, California

These Great Danes are available in San Diego, California.
We'll also keep you updated on Miss Goofy's adoption status with email updates.
Photo of Miss Goofy

Miss Goofy

Great Dane Labrador Retriever

Female, Senior
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by a community member. Why this pet is the one for you:Meet Miss Goofy, a sweet girl who is looking for a loving home to help her build confidence. She is a little shy at first, but once she gets to know you, she will melt your heart. She thrives in a patient environment where she can feel secure and gradually learn to trust. She is also looking for a family that will help her feel more comfortable with being handled. If you're able to give Goofy the extra encouragement she needs, she will blossom into a loving and loyal companion. At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for their new home! Primary Color: Black Weight: 72 Age: 8yrs 1mths 3wks
We'll also keep you updated on Odin's adoption status with email updates.
Photo of Odin

Odin

Great Dane

Male, 2 yrs
El Cajon, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Oden is a wonderful and growing Great Dane puppy. He spent the first five months of his life on a 5 to 6 foot chain. So when he arrived at the shelter, he did not have a lot of manners. But he is sweet as all get out. He is loving, playful, and just wonderful! **** Please read adoption information carefully!!!**** Odin is a stunningly handsome little boy -male, 7 months -supposedly pure-bread, -Neutered -Current Weight : 90 lbs, will grow -Crate trained -Potty trained Odin is a big, funny bundle of joy, energy, and affection. He is just a big goofball! Odin is still a puppy, and will continue to grow. He is on the bigger side, but has an abundance of affection and cuteness! Odin is a well-adjusted puppy who has been hand raised. He has never shown any signs of aggression of any kind, including food aggression, although he can occasionally be a little rambunctious. He really thinks that he is a little dog…. ? Odin wants to be a lapdog; he can’t quite figure out why he doesn’t fit in my lap, but he settles for putting his head in my lap, since the rest of him doesn’t fit 😜 Odin is used to playing and sleeping with the other dogs on the property. He is well socialized, both with humans and dogs. While I have never seen him interact with a cat, I have no reason to anticipate a problem. ************************************ ADOPTION INFORMATION ************************************ I only adopt LOCALLY; San Diego and immediate vicinity. No long distance. Certainly no out of state. I cannot respond to questions as to whether the animal is available. Please DO NOT contact me asking if the animal is available. If the dog is listed as adoptable, it is available. A home check and a background check are MANDATORY to be considered. If you are unable or unwilling to consent to these requirements, please do not apply. An adoption interview Is REQUIRED. One of our volunteers must meet and observe the dog interact with every member of the household, including pets. Preference will be given to individuals who follow the instructions AND provide complete information for adoption purposes. 1) Please go to our website ( http://aaofus.org/adoption-application.html ) 2) submit it online. Must include dog’s name and “forward to Kim” under pet’s name 3) then forward the confirmation email to me directly at animalsandkim@gmail.com That’s it: easy Peezy! You must Submit an application or at least provide written answers to the following questions in an email in order for me to respond: Must include information on EVERY person in household Number of people in household and their ages ______________________________ ____________________________________________________________ occupations ________________________________________________________________________________________ Type of residential dwelling? __________________ Rent or own? Address: __________________ __________________ __________________ Phone number: __________________ Text available? does anyone in the family suffer from allergies? ___________________ I currently own _____ dogs and _____ cats _____ other animals (please specify) their breed(s) and age(s) are as follows: ____________________________________________________________ are you willing to housebreak this pet? ________________ how will you exercise your pet ______________________ how long will your pet be left alone during the day or night _______________ where will your pet sleep ___________________________________________ do you have a door that will enable your pet to go in and out of the house freely while he is being house trained? do you have a swimming pool ?________________________________ dogs frequently dig, chew and bark - are you willing to work with the dog to stop this behavior? under what circumstance would you not be able to keep your dog? Pets can live 12 to 15 years. Would anyone be willing to help with your pet if you could no longer take care of him/her?
We'll also keep you updated on Odin's adoption status with email updates.
Photo of Odin

Odin

Great Dane

Male, Puppy
El Cajon, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Oden is a wonderful and growing Great Dane puppy. He spent the first five months of his life on a 5 to 6 foot chain. So when he arrived at the shelter, he did not have a lot of manners. But he is sweet as all get out. He is loving, playful, and just wonderful!

Or, how about these Great Danes in cities near San Diego, California

These Great Danes are available for adoption close to San Diego, California.
We'll also keep you updated on Lulu's adoption status with email updates.
Photo of Lulu

Lulu

Great Dane

Female, Adult
El Cajon, CA
Size
(when grown) -
Details
Not good with kids, Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by their previous owner on 1/26/25. Why this pet is the one for you:Lulu is a 6-year-old Great Dane with a heart as big as her size! She's dog reactive, so she'll thrive in a home without other dogs, where she can enjoy all the attention to herself. Lulu's feelings about cats are still a mystery, so it's best to keep her in a cat-free home for now. With the right family, Lulu will show just how sweet and loving she can be! At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for their new home! Primary Color: Brindle Weight: 143 Age: 6yrs 2mths 2wks
We'll also keep you updated on Lulu's adoption status with email updates.
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Lulu

Great Dane

Female, 6 yrs 3 mos
Ramona, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
*This is a courtesy listing.* Meet Lulu! 5-year-old Lulu is a beautiful, affectionate brindle Great Dane who needs a loving home after a divorce dramatically changed her living situation. She is stressed in her new environment, a small apartment with no yard. Her mom is gone up to 13 hours a day for work, and even with visits from a dog walker, Lulu is struggling to adjust to all the recent changes in her life. Lulu is a big couch potato who is very friendly, easygoing, and cuddly with adults. She loves her Lamb Chop stuffie that she carries around with her all the time. Lulu is in good health and already spayed. She goes on 2-3 walks a day around her neighborhood and also plays tug-of-war and ball for short periods of time. Lulu used to live with another dog and got along well. Since moving, she has become reactive on walks towards some dogs but not others. As a precaution, her mom doesn't walk her close to other dogs or take her to dog parks. It's possible that in a different environment with careful introductions, Lulu may again do well with other dogs. She has not been around cats. Lulu is a loving gentle giant who needs a fresh start in a calm home with outdoor space where she can stretch her long legs. She would do best in a home without young children, as their energy makes her nervous. Lulu would be fine with older, respectful children. If you have a Great Dane sized spot in your heart for this special girl, please contact Rachel via email: rachel.l.davis92@gmail.com. *Frosted Faces Foundation has not assesed this dog medically or behaviorally.*
We'll also keep you updated on Henry's adoption status with email updates.
Photo of Henry

Henry

Great Dane

Male, Adult
Escondido, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.COURTESY POST: Henry, a majestic Great Dane, is currently in need of a loving and devoted home. Abandoned at a boarding facility in Fontana, Henry has languished in their care for over a year, his heart yearning for companionship. Despite their best efforts, the boarding staff has been unable to find him a permanent home. With a heavy heart, the facility reached out for rescue assistance, but to their dismay, no rescue has yet stepped forward to offer Henry a lifeline. Henry is a gentle and affectionate soul, yearning for a one person family who understands the unique needs of his breed. While he is dog-friendly and enjoys car rides and walks on a leash, he exhibits occasional resource guarding around his favorite person, thats why the boarding facility feels he should be with just one person and be an only dog. It's definitely a behavior that stems from his extended stay in the facility. The ideal family for Henry would possess experience with Great Danes and be dedicated to providing him with the training he needs to regain his confidence and thrive. If you have the space in your home and heart to welcome this deserving boy into your life, please do not hesitate to complete our adoption application. Henry's soulful eyes and wagging tail await someone who will give him the love and security he so desperately deserves.Visit this organization's web site to see any additional information available about this pet.November 5, 2024, 9:16 pm
We'll also keep you updated on Louise's adoption status with email updates.
Photo of Louise

Louise

Great Dane Mixed Breed (Large)

Female, 3 yrs 2 mos
Carlsbad, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Read this pup’s bio on our website: https://amazingdogsrescue.org/dogs/. If the dog is not visible on our website, they are no longer available. You can meet your New Best Friend at an Adoption Event near you! Check our events calendar to see the upcoming event dates: https://amazingdogsrescue.org/events All our rescue doggies come with their health record and have received all necessary medical care, which includes (but is not limited to) all vaccines, de-wormer, anti-flea/tick medication, microchip and of course spay/neuter surgery. Our adoption fee is $500. Only in California, the fee for puppies under a year old is $600. Please consider this not as a price you pay for the doggie, but as a (partially tax-deductible) donation to our charity, so we can continue our work of saving 1000+ doggies per year. Read more about why we charge adoption fees here: https://amazingdogsrescue.org/adopt/ If you have any additional inquiries, please don't hesitate to reach out to us via call or text. We are excited to meet you at one of our upcoming adoption events! Contact before event: Sandra Garcia T (408) 477-0553. Contact at event or after adoption: Patrick Lepere T (619) 918-2142
We'll also keep you updated on Thelma's adoption status with email updates.
Photo of Thelma

Thelma

Great Dane Mixed Breed (Large)

Female, 2 yrs 1 mo
Carlsbad, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Read this pup’s bio on our website: https://amazingdogsrescue.org/dogs/. If the dog is not visible on our website, they are no longer available. You can meet your New Best Friend at an Adoption Event near you! Check our events calendar to see the upcoming event dates: https://amazingdogsrescue.org/events All our rescue doggies come with their health record and have received all necessary medical care, which includes (but is not limited to) all vaccines, de-wormer, anti-flea/tick medication, microchip and of course spay/neuter surgery. Our adoption fee is $500. Only in California, the fee for puppies under a year old is $600. Please consider this not as a price you pay for the doggie, but as a (partially tax-deductible) donation to our charity, so we can continue our work of saving 1000+ doggies per year. Read more about why we charge adoption fees here: https://amazingdogsrescue.org/adopt/ If you have any additional inquiries, please don't hesitate to reach out to us via call or text. We are excited to meet you at one of our upcoming adoption events! Contact before event: Sandra Garcia T (408) 477-0553. Contact at event or after adoption: Patrick Lepere T (619) 918-2142
We'll also keep you updated on Momzilla's adoption status with email updates.
Photo of Momzilla

Momzilla

Great Dane Weimaraner

Female, 4 yrs 6 mos
Carlsbad, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Read this pup’s bio on our website: https://amazingdogsrescue.org/dogs/. If the dog is not visible on our website, they are no longer available. You can meet your New Best Friend at an Adoption Event near you! Check our events calendar to see the upcoming event dates: https://amazingdogsrescue.org/events All our rescue doggies come with their health record and have received all necessary medical care, which includes (but is not limited to) all vaccines, de-wormer, anti-flea/tick medication, microchip and of course spay/neuter surgery. Our adoption fee is $500. Only in California, the fee for puppies under a year old is $600. Please consider this not as a price you pay for the doggie, but as a (partially tax-deductible) donation to our charity, so we can continue our work of saving 1000+ doggies per year. Read more about why we charge adoption fees here: https://amazingdogsrescue.org/adopt/ If you have any additional inquiries, please don't hesitate to reach out to us via call or text. We are excited to meet you at one of our upcoming adoption events! Contact before event: Sandra Garcia T (408) 477-0553. Contact at event or after adoption: Patrick Lepere T (619) 918-2142

These pups are in San Diego, California too!

Below are our newest added Great Danes available for adoption in San Diego, California. To see more adoptable Great Danes in San Diego, California, use the search tool below to enter specific criteria!
We'll also keep you updated on Hippo's adoption status with email updates.
Special Needs
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Hippo

Bullmastiff

Male, Adult
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Needs special attention, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Your Gentle Giant Looking for Love! Hello there, I'm Hippo, a 5-year-old Bull Mastiff mix, a big boy at 87 lbs, and neutered. I was pulled from the Riverside shelter by TAP and I am so grateful for that! I have picked up bathroom manners, working on leash manners. I have separation  anxiety and current medications to help with separation anxiety include Trazodone (~$7.00), Gabapentin (~$13.00), Acepromazine as needed (~$25.00), and Prozac (~$5.00). Monthly cost depending on where purchased and market value.  I may look imposing at first glance, but once you get to know me, you'll see I'm the sweetest and most loveable companion you could ever ask for. I love affection, and snuggling up next to my humans is one of my favorite pastimes. I'm generally friendly with other dogs, but I might need a slow introduction to make sure we're all on the same page. When I'm inside the house, I sometimes get a bit anxious and bark at people passing by, but don't worry – once we're outside, I'll mostly be an observer, calmly taking in the world around me. I can show some leash reactivity though. With some patience, understanding, and positive reinforcement training, I'm sure I can overcome this behavior. I adore outdoor adventures and walks, but I can get a little distracted if there's too much going on around me. I find night walks with minimal distractions to be the best for me. That way, I can focus on our quality time together without getting overwhelmed by everything happening around us. One of my quirks is that I like to playfully bite ankles and wrists when I want to wake you up or just engage in some playtime. I promise it's all in good fun! But for this reason, a family with older kids or adults might be a better fit for me. I would absolutely love a fun-loving home with a yard! Having a safe and secure place to play and explore would make me one happy pup! I'm quite adaptable, so whether you lead an active lifestyle or prefer a more laid-back approach, I'll fit right in. Just as long as I get plenty of love and attention, I'll be content. So, are you ready to open your heart and home to a gentle giant like me? I guarantee that with a little understanding, patience, and love, I'll be the most loyal and loving companion you could ever wish for. Let's embark on this incredible journey together, creating unforgettable memories and forging an unbreakable bond. ##1733826##
We'll also keep you updated on Lolo's adoption status with email updates.
Photo of Lolo

Lolo

Anatolian Shepherd Labrador Retriever

Male, 2 yrs 6 mos
El Cajon, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Please come to our adoption event to meet them this Saturday 5/27: PetSmart: Address: 1660 Garnet Ave, San Diego, CA 92109 - Hours: 3 to 6:pm - we may be able to see you earlier - please text us at 619-576-0747 - please text us for location and times at 619-576-0747 for our future events. If you love big puppies don't look further:) these cuties were abandoned in a box near to a canyon, left to died :( at only 6 weeks old :( There are both boys and girls in the litter and they are all beautiful! We still have Lolo and Luna - however, they do not need to be adopted together:) Now they are about 10 months old and have completed their wellness program. They have wonderful Shepherd and Retriever with all these adorable mixtures; they have a great loving temperament:) Lolo is crate trained as well and is not a barker. He is healthy, and adorable, he is eager to give you lots of love. They play wonderfully well with great big dogs, as well as dogs smaller than they are. They are ok with cats as well with a very slowly introduction. Lolo is great with kids and will make wonderful family buddies – He will be excellent for walking, running or hiking companion as well as for protection due to their size. We always take our rascals back if it isn’t a good fit. Are you ready to give him/her/them a forever home? If so, Please text at 619-576-0747 as 1st type of contact or email veronica.aaofus@gmail.com or visit our website at www.aaofus.org and complete our application at the following link: http://aaofus.org/adoption-application.html . If approved, the adoption coordinator will reach out to you to schedule a Meet-and-Greet appointment. No appointments will be made unless we have received an application; therefore, we can match you with the best fit for you. Follow us on Instagram @aaofus where you can see more pics. Please allow 48 hours to process applications and respond back to set up appointments. Unfortunately, responses back to those who do not qualify are not possible due to high volume of applications. Donation Adoption fee includes up-to-date yearly DHLPP vaccinations, spaying or neutering, deworming, flea medication, and a complementary health check up by a participating clinic near you. Please consider adopting one (or more!) of these fur babies! Due to high volume of calls; NO PHONE calls are accepted at this time - therefore, please text us or email us.- A minute of conscious - Please read:) We ask you Please to be SERIOUS adopters; as there have been so many people that are not ready. We set up meet & greet appointments, do a home visit or send them the address for some meet & greet locations, paperwork and suddenly they said they are not ready or spouse is not ready, etc. These fur kids have a very hard day the day of their appointment. Due to travelling we hold their food, so they won't get car sick. We bath them, some of them are schedule for grooming as you know it is stressful for them; then they have to travel with us picking up other rescued fur kids, and so on, it is a very stressful hard day for them for people to just cancel at last minute or not show up or do show up and just say they are not ready. Our time as well as your time is valuable. Please don't waste valuable time that is so precious for a rescued pet. Every single wasted time is a time that an animal will die because we didn't get to them on time to help them. In addition, of wasting gas and grooming fees which are paid by volunteers. Please take the time to put your shoes in the shoes of the volunteer and most of it to put your shoes on our rescued fur kids!! Please take a minute to tell yourself if you are ready to adopt and for this commitment. LIVE!! LOVE!! LAUGH!! ADOPT A RESCUED HOMELESS PET AND SAVE A LIFE!! We look forward meeting you 🐾🐾🙏❤🐕🐕🐕
We'll also keep you updated on Luna's adoption status with email updates.
Photo of Luna

Luna

Anatolian Shepherd Greyhound

Female, 3 yrs 1 mo
El Cajon, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Luna is an Anatolian Sheperd with we believe so to have greyhound as her body is developing and sosimilar to them. She is current about 70 lbs, She has a sweet temperament with everyone, loves people and she is being fostered with cats and dogs of all sizes and ages. She is 12 months old. Luna will be ideal as a running partner, hiking, camping; a sweet giant lyon, who loves to kiss you. She has received her core puppy vaccinations, dewormed, and spayed/neutered. Her human parent cannot take care of them any longer; she is sick and wants the best for them. Please open your home and hearts to our sweet and amazing mama girl:) Please contact us at 619-576-0747 as 1st type of contact or email veronica.aaofus@gmail.com or visit our website at www.aaofus.org and complete our application at the following link: http://aaofus.org/adoption-application.html . If approved, the adoption coordinator will reach out to you to schedule a Meet-and-Greet appointment. No appointments will be made unless we have received an application; therefore, we can match you with the best fit for you. Follow us on Instagram@aaofus where you can see more pics. Please allow 48 hours to process applications and respond back to set up appointments. Unfortunately, responses back to those who do not qualify are not possible due to high volume of applications. Donation Adoption fee includes up-to-date their 3 core puppy DHLPP vaccinations, spaying or neutering, deworming, flea medication, and a complementary health check up by a participating clinic near you. Please consider adopting one (or more!) of these fur babies! Due to high volume of calls; NO PHONE calls are accepted at this time - therefore, please text us or email us.- A minute of conscious - Please read:) We ask you Please to be SERIOUS adopters; as there have been so many people that are not ready. We set up meet & greet appointments, do a home visit or send them the address for some meet & greet locations, paperwork and suddenly they said they are not ready or spouse is not ready, etc. These fur kids have a very hard day the day of their appointment. Due to travelling we hold their food, so they won't get car sick. We bath them, some of them are schedule for grooming as you know it is stressful for them; then they have to travel with us picking up other rescued fur kids, and so on, it is a very stressful hard day for them for people to just cancel at last minute or not show up or do show up and just say they are not ready. Our time as well as your time is valuable. Please don't waste valuable time that is so precious for a rescued pet. Every single wasted time is a time that an animal will die because we didn't get to them on time to help them. In addition, of wasting gas and grooming fees which are paid by volunteers. Please take the time to put your shoes in the shoes of the volunteer and most of it to put your shoes on our rescued fur kids!! Please take a minute to tell yourself if you are ready to adopt and for this commitment. LIVE!! LOVE!! LAUGH!! ADOPT A RESCUED HOMELESS PET AND SAVE A LIFE!! Less

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in San Diego, California.

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Great Dane shelters & rescues in San Diego, California

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in San Diego, California. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Shelter

3.6 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

9.5 miles

Animal Advocates of the US - San Diego Chapter

El Cajon, CA 92122

Pet Types: cats, dogs, rabbits

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Shelter

12.5 miles

San Diego Humane Society - El Cajon Campus

1373 N. Marshall Ave., El Cajon, CA 92020

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

27.2 miles

Frosted Faces Foundation

1448 Pine St, Ramona, CA 92065

Pet Types: cats, dogs

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Rescue

29.4 miles

TLC K9 Rescue

Escondido, CA 92027

Pet Types: dogs

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Rescue

30.9 miles

Amazing Dogs

Carlsbad, CA 92011

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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