No, there’s no such thing as a truly hypoallergenic dog. Mutts are less likely to trigger your allergies if their parents were a breed (or combination of breeds) such as Poodle, Bichon Frise, Maltese, Afghan Hound, Portuguese Water Dog or other breeds known for being “hypoallergenic.” Since it’s difficult to tell which breeds may be in a mixed-breed dog’s background based on their appearance, assessing whether a mutt is hypoallergenic can be almost impossible. A doggie DNA test, such as Wisdom Panel, could help.
But while some breeds are often considered “hypoallergenic” due to their low-shedding coats, it’s important to understand that the main allergen for many people is actually a protein found in dog saliva and dander (skin flakes), not the fur itself. So, even if a mutt has a low-shedding coat, they can still trigger allergies in some individuals.