How long do Tosa Inus live?

Tosa Inus typically live about 10 to 12 years. When compared to the lifespans of similar breeds like Mastiffs (six to 10 years) or Great Danes (seven to 10 years), Tosa Inus tend to live a bit longer. 

Factors that can affect their longevity include proper diet, regular exercise, and routine vet care to prevent or properly manage conditions like heart problems. Larger breeds generally tend to have shorter lifespans due to the strain their size puts on their joints and organs, so keeping them at a healthy weight and watching for signs of early arthritis or other conditions can help extend their lifespan.